Dr Comrie graduated from RMIT University in 1994. He spent 3 months after graduation at the Royal Saskatoon Hospital, Saskatchewan, Canada observing David Cassidy, Pierre Cote, and medical specialists at the hospital. In 1995 he commenced work as an associate at the Heidelberg Chiropractic Clinic and took over as principal in 2000. His practice focuses on general chiropractic practice and incorporating evidence-based practice with low tech rehabilitation.
Dr Comrie is a founding Board member and current Vice President of Chiropractic Australia and formerly held positions as secretary and president of the Chiropractic & Osteopathic College of Australasia after joining the Board in 1997. In 2018 he was awarded Life Membership for his contribution to both organisations.