Nocebo

Nocebo hyperalgesia can be induced by classical conditioning without involvement of expectancy. Bajcar EA, Adamczyk WM, Wiercioch-Kuzianik K, Bąbel P. PLoS One. 2020 May 7;15(5):e0232108. doi: 10.1371/journal.pone.0232108. Can Positive Framing Reduce Nocebo Side Effects? Current Evidence and Recommendation for Future Research. Barnes K, Faasse K, Geers AL, Helfer SG, Sharpe L, Colloca L, Colagiuri B. Front Pharmacol. 2019 Mar 6;10:167. doi: 10.3389/fphar.2019.00167. Autonomic Arousal as a Mechanism of the Persistence of Nocebo Hyperalgesia Ben Colagiuri, Veronica F. Quinn. The Journal of Pain. December 18, 2017. DOI:10.1016/j.jpain.2017.12.006 Interactions between brain and spinal cord mediate value effects in nocebo hyperalgesia. Tinnermann A, Geuter S, Sprenger C, Finsterbusch J, Büchel C. Science. 2017 Oct 6;358(6359):105-108. doi: 10.1126/science.aan1221. Nocebo and pain: an overview of the psychoneurobiological mechanisms  Blasini, Maxie; Corsi, Nicole; Klinger, Regine; More  PAIN Reports . 2(2):e585, March/April 2017. doi: 10.1097/PR9.0000000000000585 Nocebo effects in clinical studies: hints for pain therapy Klinger, Regine; Blasini, Maxie; Schmitz, Julia; More  PAIN Reports . 2(2):e586, March/April 2017. doi: 10.1097/PR9.0000000000000586 Placebo and Nocebo Effects: The Advantage of Measuring Expectations and Psychological Factors. Corsi N, Colloca L. Front Psychol. 2017 Mar 6;8:308. doi: 10.3389/fpsyg.2017.00308. Psychological Placebo and Nocebo Effects on Pain Rely on Expectation and Previous Experience. http://www.ncbi.nlm.nih.gov/pubmed/26523863  Fear of pain potentiates nocebo hyperalgesia https://www.dovepress.com/fear-of-pain-potentiates-nocebo-hyperalgesia-peer-reviewed-fulltext-article-JPR Nocebo context modulates long-term habituation to heat pain and influences functional connectivity of the operculum. http://www.ncbi.nlm.nih.gov/pubmed/26181304  Neural underpinnings of nocebo hyperalgesia in visceral pain: A fMRI study in healthy volunteers. http://www.ncbi.nlm.nih.gov/pubmed/26123378  Modulation of Inhibitory Corticospinal Circuits Induced by a Nocebo Procedure in Motor Performance http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125223 Nocebo vs. placebo: the challenges of trial design in analgesia research. http://www.ncbi.nlm.nih.gov/pubmed/25670519 The magnitude of nocebo effects in pain: A meta-analysis http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213146  Facilitation of Pain in the Human Spinal Cord by Nocebo Treatment http://www.jneurosci.org/content/33/34/13784.full Nocebo Phenomena in Medicine: Their Relevance in Everyday Clinical Practice http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401955/?tool=pmcentrez  The nocebo effect and its relevance for clinical practice http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167012/?tool=pmcentrez 

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